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Antileishmanial agent 17

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149958
    Antileishmanial agent-17

    		Parasite Infection
    Antileishmanial agent-17 is a coumarin hybrid compound with antileishmanial effects (IC50 <0.78 μM). Antileishmanial agent-17 is safe to normal VERO cells. Antileishmanial agent-17 binds to folate pathway enzymes pteridine reductase and DHFR-TS. And Antileishmanial agent-17 shows the most potent with IC50 value of 0.40 μM against promastigote and 0.68 μM against amastigote, respectivley.
    <em>Antileishmanial</em> <em>agent-17</em>

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